How does DNA fold The loop extrusion model
The human genome is two meters long but fits inside the microscopic nucleus of a cell. How does it do this Our work suggests that the genome forms loops and domains through a process called extrusion For more information, see Chromatin extrusion explains key features of loop and domain formation in wildtype and engineered Sanborn and Rao et al. , PNAS 2015. Directed by Adrian Sanborn and Erez Aiden Animated by Najeeb Tarazi Narrated by
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