Bonnie Bassler ( Princeton) Part 2: Vibrio Cholerae Quorum Sensing and Novel Antibiotics

Bacteria, primitive singlecelled organisms, communicate with chemical languages that allow them to synchronize their behavior and thereby act as enormous multicellular organisms. This process is called quorum sensing and it enables bacteria to successfully infect and cause disease in plants, animals, and humans. Investigations of the molecular mechanisms underlying quorum sensing are leading to the development of novel strategies to interfere w