Solving chromosomes structure

Scientists first discovered chromosomes in the late 1800s, after the light microscope was invented. Using these microscopes, biologist Walter Flemming observed many tightly wound, elongated structures in cell nuclei. Later, it was found that chromosomes are made from DNA, the cell s genetic material. Since then, scientists have proposed many possible ways that DNA molecules might fold into 3D condensed chromosomes. Now, researchers at MIT and the University of Massachusetts Medical School have obta