PINK1, Parkin derails damaged mitochondria

Thomas Schwarz shows how Parkinson s disease proteins quarantine damaged mitochondria by disconnecting them from the microtubule network. Check out the paper at Wang, X., Winter, D., Ashrafi, G., Schlehe, J., Wong, Y. L., Selkoe, D., Rice, S., Steen, J., LaVoie, M. J., and Schwarz, T. L. (2011). PINK1 and Parkin Target Miro for Phosphorylation and Degradation to Arrest Mitochondrial Motility. Cell. 147 And read more great research at