What Student Need to Know about X Linked Gene Inheritance

Over 130 Xlinked genes have been robustly associated with developmental disorders, and Xlinked causes have been hypothesised to underlie the higher developmental disorder rates in males. Xlinked is a trait where a gene is located on the X chromosome. Humans and other mammals have two sex chromosomes, the X and the Y. In an Xlinked or sex linked disease, it is usually males that are affected because they have a single copy of the X chromosome that carries the mutation. In females, the effect of the mutation may be masked by the second healthy copy of the X chromosome. Xlinked inheritance patterns differ depending on the type of inheritance. Recessive X linked conditions are always passed through the maternal line with the condition appearing in males and being carried in females, but not usually expressed. Dominant Xlinked conditions can be passed from either affected parent to their children. If the father has the affected copy of the gene he will only pass the condition to his daughters and not his