Introduction to Cancer Biology ( Part 1): Abnormal Signal Transduction

This animation is the first part of the series An Introduction to Cancer Biology, and explains the mechanism of abnormal signal transduction resulting in uncontrolled cell proliferation. This animation also provides an overview of the potential targets of anticancer therapies. REFERENCES: 1. Hanahan D, Weinberg RA. The hallmarks of cancer. Cell. 2000 Jan 7; 100(1):5770. 2. Herbst RS. Review of epidermal growth factor receptor biology. Int J Radiat Oncol Biol Phys. 2004; 59(2 Suppl):216. 3. Gerharz CD,